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Herpes simplex virus 1 (cold sores) and 2 (genital herpes) (HSV-1 and HSV-2) are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. [1] [2] Both HSV-1 and HSV-2 are very common and contagious. They can be spread when an infected person begins shedding the virus.
Herpes simplex, often known simply as herpes, is a viral infection caused by the herpes simplex virus. [5] Herpes infections are categorized by the area of the body that is infected. The two major types of herpes are oral herpes and genital herpes, though other forms also exist. Oral herpes involves the face or mouth.
Herpes simplex virus 1 infects humans, most often as cold sores. It is very common and contagious; about 67% of the world population under the age of 50 has Herpes simplex virus 1. [5] It is often acquired orally during childhood.
More than 3.7 billion people under the age of 50 suffer from the herpes simplex virus type 1 (HSV-1), usually after catching it in childhood.
It is estimated to affect at least 1 in 500,000 individuals per year, [1] and some studies suggest an incidence rate of 5.9 cases per 100,000 live births. [2] About 90% of cases of herpes encephalitis are caused by herpes simplex virus-1 (HSV-1), the same virus that causes cold sores.
Herpes labialis infection occurs when the herpes simplex virus comes into contact with oral mucosal tissue or abraded skin of the mouth. [17] Infection by the type 1 strain of herpes simplex virus (HSV-1) is most common; however, cases of oral infection by the type 2 strain are increasing. [14]