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HCCC consist of cells with abundant clear cytoplasm, arranged in cords, trabeculae or clusters in a hyalinized stroma. [3] Nuclear pleomorphism is usually minimal and mitoses are infrequently seen. [2] Owing to their glycogen content, which explains the "clear" appearance under the microscope, tumour cells stain with PAS.
Fibroadenoma of the breast is a benign tumor composed of a biplastic proliferation of both stromal and epithelial components. [ 12 ] [ 13 ] This biplasia can be arranged in two growth patterns: pericanalicular (stromal proliferation around epithelial structures) and intracanalicular (stromal proliferation compressing the epithelial structures ...
This condition is characterised by abnormal growth of hyalinized fibrous tissue with cutaneous, mucosal, osteoarticular and systemic involvement. Clinical features include extreme pain at minimal handling in a newborn, gingival hypertrophy, subcutaneous nodules, painful joint stiffness and contractures, muscle weakness and hypotonia.
For comparison, this is about 15 years older than the typical age of patients with a fibroadenoma, a common differential diagnosis in patients with a suspected phyllodes tumors. [26] Younger women have a higher chance of having a benign phyllodes tumor, while older women are more likely to have higher-grade tumors.
Micrograph showing the characteristic hyalinized papillary cores found in some hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cell carcinomas. H&E stain . Hereditary leiomyomatosis and renal cell carcinoma ( HLRCC ) or Reed's syndrome is rare autosomal dominant disorder associated with benign smooth muscle tumors ...
Given their mesothelial origin, the cells lining the spaces are positive for cytokeratins, WT1, D2-40, and calretinin.They are negative for MOC31, BerEP4, and vascular markers (CD31 or CD34).
Cutaneous myxoma appears as a little, slowly expanding dermal or subcutaneous lump that typically affects adults' heads and necks. [3] Alopecic lesions have been reported, [4] [5] characterized by hair tufts overlaying the lesion or even hypertrichosis. [6]
Main staining types when using hematoxylin and eosin (H&E). A Basophil granulocyte stains dark purple upon H&E staining.. Basophilic is a technical term used by pathologists. ...