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He postulated the limbic system as the brain's center of emotions, including the hippocampus and amygdala. Developing observations made by Papez, he hypothesized that the limbic system had evolved in early mammals to control fight-or-flight responses and react to both emotionally pleasurable and painful sensations.
The amygdala (/ ə ˈ m ɪ ɡ d ə l ə /; pl.: amygdalae / ə ˈ m ɪ ɡ d ə l i,-l aɪ / or amygdalas; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'almond', 'tonsil' [1]) is a paired nuclear complex present in the cerebral hemispheres of vertebrates. It is considered part of the limbic system. [2]
A photograph of the inferior medial view of the brain when dissected clearly shows the layout of the Papez circuit. Due to the location of the structures in the circuit, the resulting shape is a limbus. This is what drove MacLean to call the circuit the limbic system when he later modified the circuit.
It leads from the basolateral nucleus and central nucleus of the amygdala. The amygdala is a limbic structure in the medial temporal lobe of the brain. The other main efferent pathways from the amygdala are the stria terminalis and anterior commissure.
Amygdala (limbic system) (limbic lobe) Central nucleus (autonomic nervous system) Medial nucleus (accessory olfactory system) Cortical and basomedial nuclei (main olfactory system) Lateral and basolateral nuclei (frontotemporal cortical system) Extended amygdala. Stria terminalis. Bed nucleus of the stria terminalis; Claustrum; Basal ganglia ...
This region is extremely rich in serotonin transporters and is considered as a governor for a vast network involving areas like hypothalamus and brain stem, which influences changes in appetite and sleep; the amygdala and insula, which affect the mood and anxiety; the hippocampus, which plays an important role in memory formation; and some parts of the frontal cortex responsible for self ...
The uncinate fasciculus is a bi-directional pathway between the temporal lobe and frontal lobe; it is traditionally considered to be part of the limbic system. [2] It has been proposed that the uncinate fasciculus allows mnemonic representations stored in the temporal lobe to interact with and guide decision making in the frontal lobe. [4]
They are located on the undersurface of the brain that, as part of the diencephalon, form part of the limbic system. They are located at the ends of the anterior arches of the fornix. [3] They consist of two groups of nuclei, the medial mammillary nuclei and the lateral mammillary nuclei. [4]