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A biosafety cabinet (BSC)—also called a biological safety cabinet or microbiological safety cabinet—is an enclosed, ventilated laboratory workspace for safely working with materials contaminated with (or potentially contaminated with) pathogens requiring a defined biosafety level.
CDC technician dons an older-model positive-pressure suit before entering one of the CDC's earlier BSL-4 labs. Biosafety level 4 (BSL-4) is the highest level of biosafety precautions, and is appropriate for work with agents that could easily be aerosol-transmitted within the laboratory and cause severe to fatal disease in humans for which there ...
BSL-4 cabinets and "Suit Laboratories" have special engineering and design features to prevent hazardous microorganisms from being disseminated into the outside environment. These biosafety suites , where PPPSs are used, are suites of laboratory rooms which are essentially equivalent to large Class III biosafety cabinets in which the interiors ...
A PAPR, gown, and biosafety cabinet in use in a BSL-3 laboratory. All parts of the PAPR are visible: the waist unit holding the fan, filter, and battery; the hose; and the mask, in this case a flexible, loose-fitting one. A powered air-purifying respirator (PAPR) is a type of respirator used to safeguard workers against contaminated air.
NEIDL is one of only 13 operational or planned biosafety level 4 (BSL-4) laboratories in the United States. NEIDL's current director is Nancy Sullivan, ScD . She previously served as the chief of the Biosecurity Research Section at the Vaccine Research Center of the National Institute of Allergy and Infectious Diseases (NIAID) in the National ...
A biosafety cabinet is also easily-confused with a laminar flow cabinet, but like the fume hood is primarily designed to protect the worker rather than the biological samples. This is achieved by drawing surrounding air in and exhausting it through a HEPA filter to remove potentially hazardous microorganisms.