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Principles of D-dimer testing. Fibrin degradation products (FDPs), also known as fibrin split products, are components of the blood produced by clot degeneration. [1] Clotting, also called coagulation, at the wound site produces a mass of fibrin threads called a net that remains in place until the cut is healed. As a cut heals, the clotting ...
D-dimer (or D dimer) is a dimer that is a fibrin degradation product (FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two D fragments of the fibrin protein joined by a cross-link , hence forming a protein dimer .
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Those who finish warfarin treatment after idiopathic VTE with an elevated D-dimer level show an increased risk of recurrent VTE (about 9% vs about 4% for normal results), and this result might be used in clinical decision making. [133] Thrombophilia test results rarely play a role in the length of treatment. [80]
A measurement of blood D-dimer level may be useful in diagnostic evaluation. A level less than 500 ng/ml may be considered evidence against a diagnosis of aortic dissection, [1] [31] although this guideline is only applicable in cases deemed "low risk" [32] and within 24 hours of symptom onset. [33]
In biochemistry, a protein dimer is a macromolecular complex or multimer formed by two protein monomers, or single proteins, which are usually non-covalently bound. Many macromolecules, such as proteins or nucleic acids, form dimers. The word dimer has roots meaning "two parts", di-+ -mer. A protein dimer is a type of protein quaternary structure.
For example, acetic acid forms a dimer in the gas phase, where the monomer units are held together by hydrogen bonds. [3] Many OH-containing molecules form dimers, e.g. the water dimer . Dimers that form based on weak electrostatic interaction and/or van der Waals interactions have a short lifetime, but can be stabilized through special ...
Dimer may refer to: Dimer (chemistry), a chemical structure formed from two similar sub-units Protein dimer, a protein quaternary structure; d-dimer; TH-dimer;