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Hypothyroidism is the most frequent endocrine disorder. [43] Worldwide about one billion people are estimated to be iodine deficient; however, it is unknown how often this results in hypothyroidism. [11] In large population-based studies in Western countries with sufficient dietary iodine, 0.3–0.4% of the population have overt hypothyroidism.
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Thyroid diseases are highly prevalent worldwide, [10] [11] [12] and treatment varies based on the disorder. Levothyroxine is the mainstay of treatment for people with hypothyroidism, [13] while people with hyperthyroidism caused by Graves' disease can be managed with iodine therapy, antithyroid medication, or surgical removal of the thyroid ...
The severity of these symptoms are determined by the period of hypothyroidism and the degree of deficiency of thyroid hormones. [10] It may also include macroglossia. [11] EMG is either normal or may show myopathic low amplitude and short duration motor unit action potentials (MUAPS). [12] The enzymes creatine kinase is elevated usually.
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Iodine deficiency causes gradual enlargement of the thyroid gland, referred to as a goiter. Poor length growth is apparent as early as the first year of life. Adult stature without treatment ranges from 100 to 160 cm (3 ft 3 in to 5 ft 3 in), depending on severity, sex, and other genetic factors.
The diagnosis of hypothyroidism, when suspected, can be confirmed with blood tests measuring thyroid-stimulating hormone (TSH) and thyroxine levels. [1] People over the age of 60 are more commonly affected.