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Moderately or severely immunocompromised patients who have gotten COVID-19 vaccines before Sept. 12, 2023, should get one or two doses of the updated vaccine depending on previous doses and age.
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), or Shoenfeld's syndrome, is a hypothesised autoimmune disorder proposed by Israeli immunologist Yehuda Shoenfeld in 2011. [1] According to Shoenfeld, the syndrome is triggered by exposure to adjuvants and includes four conditions: " post-vaccination symptoms ", macrophagic ...
Disease experts say it has become increasingly clear that an autoimmune response, in which antibodies attack the body’s own healthy cells and tissue, plays an important role in some long-Covid ...
In the earliest days of the pandemic, many immunologists, including me, assumed that patients who produced high quantities of antibodies early in infection would be free from disease. We were ...
The EMA also initiated an assessment for all COVID‑19 vaccines used in the EU for immune thrombocytopenia (ITP), described as low blood platelet levels that could lead to bruising and bleeding, as a possible side effect, whilst also stating that up to this point no link with any COVID‑19 had been established. [12]
As of April 2020 trials were investigating whether existing medications could be used effectively against the body's immune reaction to SARS-CoV-2 infection. [44] [45] As of May 2020 several antiviral drugs were under investigation for COVID-19, though none had been shown to be clearly effective on mortality in published randomized controlled ...
New research may finally answer why long COVID patients are still sick, suggesting one "auto-antibody" may be responsible for harmful inflammation. Scientists are getting closer to classifying ...
Vaccine efficacy is the reduction in risk of getting the disease by vaccinated participants in a controlled trial compared with the risk of getting the disease by unvaccinated participants. [346] An efficacy of 0% means that the vaccine does not work (identical to placebo).