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Cryptorchidism, also known as undescended testis, is the failure of one or both testes to descend into the scrotum. The word is from Ancient Greek ...
The most common presentation of testicular cancer is a hard, painless lump which can be felt on one of the testis. It is either noticed by a clinician during a routine examination, or the patient themselves. [17] Risk factors for TC include: Cryptorchidism; Family history; Previous testicular cancer; The diagnosis is confirmed in different ways.
The lower part persists as the gubernaculum testis ("scrotal ligament"). This ligament secures the testis to the most inferior portion of the scrotum, tethering it in place and limiting the degree to which the testis can move within the scrotum. Cryptorchidism (undescended testes) are observed in INSL3-null male mice.
Manifestations of mixed gonadal dysgenesis are highly variable with asymmetry in gonadal development of testis and streak gonad, accounted for by the percentage of cells expressing XY genotype. [22] [23] The dysgenic testis can have an amount of functional tissue which can produce a level of testosterone, which causes masculinisation. [22] [23]
This is an accepted version of this page This is the latest accepted revision, reviewed on 15 February 2025. Sac of skin that protects the testicles For the obsolete dinosaur fossil name, see Megalosaurus § "Scrotum humanum". Scrotum A human's scrotum in a relaxed state (left) and a tense state (right) Details Precursor Labioscrotal swellings System Reproductive system Artery Anterior scrotal ...
The undescended testis is at increased risk of testicular torsion. [17] The mechanism for torsion in the undescended testicle is not fully understood, though it may be due to abnormal contractions of the cremaster muscle, which covers the testicle and spermatic cord and is responsible for raising and lowering the testicle to regulate scrotal ...
Orchiopexy is performed in the event of testicular torsion, a urologic emergency presenting with intense pain and often without inciting injury. [citation needed]While neonatal torsion occurs with no anatomic defect to account for its occurrence (occurring in utero or shortly after birth), adult torsion results from a bilateral congenital anomaly often called a "bell-clapper deformity", where ...
FMRP is made from the FMR1 gene and is mainly in the brain and testis. They used the analysis of covariance (ANCOVA) to compare the IQs of the macroorchidism patients with and without pre-mutation carriers. The results showed that there is a relationship between macroorchidism and intellectual disability in FMR1 pre-mutation carrier males.