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Severe gingivitis in dogs can further advance into periodontal disease in which the periodontal tissues begin to degrade and, if left untreated, can lead to tooth loss. [11] Studies have also shown that periodontal disease can negatively affect systemic health which impacts the overall health of the dog, therefore exhibiting the importance of ...
Researchers from Ben-Gurion University of the Negev, in collaboration with teams from Sichuan University and the National University of Singapore, have identified that 3,3′-Diindolylmethane (DIM) – a naturally occurring molecule also referred to as bisindole – can reduce biofilms responsible for plaque and cavities by a remarkable 90%. [7]
The C2DA inhibit methicillin resistant staphylococcus biofilm, but don't eliminate it. The mechanism of the biofilm inhibition by these molecules is still unknown. C2D is a medium of fatty acid chain that effect on staphylococcus aureus biofilm and dispersion of these biofilm. Pseudomonas aeruginosa is the main source for these molecules. [15]
Various commercially available mouth rinses have been tested for their inhibitory effects on biofilm formation over a 24-hour period. [3] By slowing the formation of biofilms, individuals who use Biotène may reduce the risk of dental caries and other oral diseases that can arise from xerostomia and bacterial accumulation, thus improving both ...
To prevent demineralisation in the mouth, it is important for an individual to ensure they have a well-balanced diet, including foods containing calcium and foods that are low in acids and sugars. The individual should have a diet high in fresh fruits and vegetables, wholegrain cereals, legumes, seeds and nuts.
Thin-film drug delivery uses a dissolving film or oral drug strip to administer drugs via absorption in the mouth (buccally or sublingually) and/or via the small intestines (enterically). A film is prepared using hydrophilic polymers that rapidly dissolves on the tongue or buccal cavity, delivering the drug to the systemic circulation via ...