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Although clinically debated, [6] [7] the Dutch hypothesis remains one of four main plausible explanations which could help explain the complex pathogenesis of COPD, others being the protease-antiprotease hypothesis (involving alpha 1-antitrypsin overexpression and consequent alpha-1 proteinase deficiency), the British hypothesis (regarding a ...
Gordon didn’t know at the time that this episode was caused by COPD, a progressive disease that damages lungs and makes it hard to breathe. 1 Looking back, he recognizes there were many missed ...
A representation by Robert Seymour of the cholera epidemic depicts the spread of the disease in the form of poisonous air.. The miasma theory was the predominant theory of disease transmission before the germ theory took hold towards the end of the 19th century; it is no longer accepted as a correct explanation for disease by the scientific community.
This began the path to germ specificity within the theory. [49] Louis Pasteur's contemporary Robert Koch devoted much of his scientific study to discovering certain pathogens and connecting them to specific diseases. These scientists were often in competition with one another and so the Koch-Pasteur rivalry is a well-known part of germ theory's ...
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...
Ewald is known for his "theory of virulence”, suggesting that "the deadlier the germ, the less likely it is to spread", [1] and his theory that many common diseases of unknown origin are likely the result of chronic low-level infections from viruses, bacteria or protozoa.
Association for Professionals in Infection Control and Epidemiology is primarily composed of infection prevention and control professionals with nursing or medical technology backgrounds; The Society for Healthcare Epidemiology of America is more heavily weighted towards practitioners who are physicians or doctoral-level epidemiologists.
Plague Time: The New Germ Theory of Disease is a non-fiction book by evolutionary biologist Paul W. Ewald. It argues that the role of pathogens has been overlooked in medicine, as a primary cause of many chronic diseases. It is his second book, following Evolution of Infectious Disease in 1994.