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Cryptococcus neoformans is an encapsulated basidiomycetous yeast [1] belonging to the class Tremellomycetes and an obligate aerobe [2] that can live in both plants and animals. Its teleomorph is a filamentous fungus , formerly referred to Filobasidiella neoformans .
Cryptococcus is a genus of fungi in the family Cryptococcaceae that includes both yeasts and filamentous species. The filamentous, sexual forms or teleomorphs were formerly classified in the genus Filobasidiella, while Cryptococcus was reserved for the yeasts. Most yeast species formerly referred to Cryptococcus have
Cryptococcus gattii, formerly known as Cryptococcus neoformans var. gattii, is an encapsulated yeast found primarily in tropical and subtropical climates. Its teleomorph is Filobasidiella bacillispora , a filamentous fungus belonging to the class Tremellomycetes .
However, there are examples of animal and human parasites where the species are dimorphic but it is the yeast-like state that is infectious. [18] The genus Filobasidiella forms basidia on hyphae but the main infectious stage is more commonly known by the anamorphic yeast name Cryptococcus, e.g. Cryptococcus neoformans [19] and Cryptococcus ...
Cryptococcus neoformans is a basidiomycetous fungus that grows as a budding yeast in culture and infected hosts. C. neoformans causes life-threatening meningoencephalitis in immunocompromised patients. It undergoes a filamentous transition during the sexual cycle to produce spores, the suspected infectious agent.
Cryptococcosis is a potentially fatal fungal infection of mainly the lungs, presenting as a pneumonia, and in the brain, where it appears as a meningitis. [4] [9] [12] Coughing, difficulty breathing, chest pain and fever are seen when the lungs are infected. [5]
The majority of Cryptococcus species live in the soil and do not cause disease in humans. Cryptococcus neoformans is the major human and animal pathogen. Papiliotrema laurentii and Naganishia albida, both formerly referred to Cryptococcus, have been known to occasionally cause moderate-to-severe disease in human patients with compromised immunity.
A blastoconidium (plural blastoconidia) is an asexual holoblastic conidia formed through the blowing out or budding process of a yeast cell, which is a type of asexual reproduction that results in a bud arising from a parent cell. [1] [2] The production of a blastoconidium can occur along a true hyphae, pseudohyphae, or a singular yeast cell. [3]