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  2. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    CRISPR gene editing (CRISPR, pronounced / ˈ k r ɪ s p ə r / (crisper), refers to a clustered regularly interspaced short palindromic repeats") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified.

  3. CRISPR interference - Wikipedia

    en.wikipedia.org/wiki/CRISPR_interference

    CRISPR interference (CRISPRi) is a genetic perturbation technique that allows for sequence-specific repression of gene expression in prokaryotic and eukaryotic cells. [1] It was first developed by Stanley Qi and colleagues in the laboratories of Wendell Lim , Adam Arkin, Jonathan Weissman , and Jennifer Doudna . [ 2 ]

  4. CRISPR activation - Wikipedia

    en.wikipedia.org/wiki/CRISPR_activation

    Unlike traditional CRISPR-Cas9, which introduces double-strand breaks to edit genes, CRISPRa employs a modified, catalytically inactive Cas9 (dCas9) fused with transcriptional activators to target promoter or enhancer regions, thereby boosting gene transcription. This method allows for precise control of gene expression, making it a valuable ...

  5. Engineer explains how Nobel Prize-winning CRISPR ... - AOL

    www.aol.com/news/engineer-explains-nobel-prize...

    Researchers have been able to manipulate large chunks of genetic code for almost 50 years. This newfound ability is called gene-editing, the tool is called CRISPR, and it’s being used worldwide ...

  6. CRISPR - Wikipedia

    en.wikipedia.org/wiki/CRISPR

    CRISPR gene editing is a revolutionary technology that allows for precise, targeted modifications to the DNA of living organisms. Developed from a natural defense mechanism found in bacteria, CRISPR-Cas9 is the most commonly used system.

  7. Guide RNA - Wikipedia

    en.wikipedia.org/wiki/Guide_RNA

    CRISPR (Clustered regularly interspaced short palindromic repeats)/Cas9 is a technique used for gene editing and gene therapy. Cas is an endonuclease enzyme that cuts DNA at a specific location directed by a guide RNA.

  8. Here’s what a Nobel Prize-winning scientist wants you ... - AOL

    www.aol.com/nobel-prize-winning-scientist-breaks...

    In his new book “The Catalyst,” Thomas R. Cech talks about the Covid-19 vaccines, what RNA means for future health crises and how gene editing with CRISPR factors in.

  9. Gene drive - Wikipedia

    en.wikipedia.org/wiki/Gene_drive

    Typically, scientists insert the gene drive into an organism's DNA along with the CRISPR-Cas9 machinery. When the modified organism mates and its DNA mixes with that of its mate, the CRISPR-Cas9 tool cuts the partner's DNA at the same spot where the gene drive is located in the first organism.