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Melanocytes are melanin-producing neural crest-derived [3] cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), [4] the inner ear, [5] vaginal epithelium, [6] meninges, [7] bones, [8] and heart found in many mammals and birds. [9] Melanin is a dark pigment primarily responsible ...
Arachnids are one of the few groups in which melanin has not been easily detected, though researchers found data suggesting spiders do in fact produce melanin. [46] Some moth species, including the wood tiger moth, convert resources to melanin to enhance their thermoregulation. As the wood tiger moth has populations over a large range of ...
Along the junction of the epidermis and the underlying dermis. [15] May be colored and slightly raised. [16] ICD10: D22 ICDO: M8740/0 Compound nevus Both the epidermis and dermis. [17] ICD10: D22 (ILDS D22.L14) ICDO: 8760/0 Intradermal nevus Within the dermis. A classic mole or birthmark. It typically appears as an elevated, dome-shaped bump on ...
The dermis contains two vascular networks that run parallel to the skin surface—one superficial and one deep plexus—which are connected by vertical communicating vessels. [8] [11] The function of blood vessels within the dermis is fourfold: to supply nutrition, to regulate temperature, to modulate inflammation, and to participate in wound ...
Micrograph of keratinocytes, basal cells and melanocytes in the epidermis Keratinocytes (stained green) in the skin of a mouse. Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. In humans, they constitute 90% of epidermal skin cells. [1]
It is a harmless (benign) hyperplasia of melanocytes which is linear in its spread. This means the hyperplasia of melanocytes is restricted to the cell layer directly above the basement membrane of the epidermis where melanocytes normally reside. This is in contrast to the "nests" of multi-layer melanocytes found in moles (melanocytic nevi ...
Mongolian spot is a congenital developmental condition—that is, one existing from birth—exclusively involving the skin.The blue colour is caused by melanocytes, melanin-containing cells, that are usually located in the surface of the skin (the epidermis), but are in the deeper region (the dermis) in the location of the spot. [6]
The word itself comes from the Greek words chrōma (χρῶμα) meaning "colour," and phoros (φόρος) meaning "bearing". In contrast, the word chromatocyte (kytos (κύτος) meaning "cell") was adopted for the cells responsible for colour found in birds and mammals. Only one such cell type, the melanocyte, has been identified in these ...