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2-Methylimidazole (1) may be prepared via the Debus-Radziszewski imidazole synthesis, or from ethylenediamine and acetic acid, followed by treatment with lime, then Raney nickel. 2-Methylimidazole is nitrated to give 2-methyl-4(5)-nitroimidazole (2), which is in turn alkylated with ethylene oxide or 2-chloroethanol to give metronidazole (3 ...
Nystatin, sold under the brand name Mycostatin among others, is an antifungal medication. [1] It is used to treat Candida infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. [1] It may also be used to prevent candidiasis in those who are at high risk. [1]
Gel conditions are 1% agarose, 3 volt/cm, and ethidium bromide stain. A molecular-weight size marker , also referred to as a protein ladder , DNA ladder , or RNA ladder , is a set of standards that are used to identify the approximate size of a molecule run on a gel during electrophoresis , using the principle that molecular weight is inversely ...
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Miconazole is partly absorbed in the intestinal tract when used orally, as with the oral gel, and possibly when used vaginally. [9] This can lead to increased concentrations of drugs that are metabolized by the liver enzymes CYP3A4 and CYP2C9, because miconazole inhibits these enzymes.
Ketoconazole 2% gel Ketoconazole shampoo in conjunction with an oral 5α-reductase inhibitor such as finasteride or dutasteride has been used off label to treat androgenic alopecia . It was speculated that antifungal properties of ketoconazole reduce scalp microflora and consequently may reduce follicular inflammation that contributes to alopecia.
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