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  2. Foramen ovale (heart) - Wikipedia

    en.wikipedia.org/wiki/Foramen_ovale_(heart)

    The foramen ovale (from Latin 'oval hole') forms in the late fourth week of gestation, as a small passageway between the septum secundum and the ostium secundum. Initially the atria are separated from one another by the septum primum except for a small opening below the septum, the ostium primum .

  3. Atrial septal defect - Wikipedia

    en.wikipedia.org/wiki/Atrial_septal_defect

    Atrial septal defect (ASD) is a congenital heart defect in which blood flows between the atria (upper chambers) of the heart.Some flow is a normal condition both pre-birth and immediately post-birth via the foramen ovale; however, when this does not naturally close after birth it is referred to as a patent (open) foramen ovale (PFO).

  4. Fossa ovalis (heart) - Wikipedia

    en.wikipedia.org/wiki/Fossa_ovalis_(heart)

    If the atrial septum does not close properly, it leads to a patent foramen ovale (PFO). This type of defect generally works like a flap valve, opening during certain conditions of increased pressure in the chest, such as during strain while having a bowel movement, cough, or sneeze.

  5. Woman who had a heart attack at 24 reveals the firsts ...

    www.aol.com/news/woman-24-had-heart-attack...

    “We recently found something called a (patent foramen ovale) PFO, which is … a moderate to large hole in my heart.” ... But for about 25% of people, the opening doesn't close, the American ...

  6. Decompression sickness - Wikipedia

    en.wikipedia.org/wiki/Decompression_sickness

    patent foramen ovale – a hole between the atrial chambers of the heart in the fetus is normally closed by a flap with the first breaths at birth. In about 20% of adults the flap does not completely seal, however, allowing blood through the hole when coughing or during activities that raise chest pressure.

  7. Valve of inferior vena cava - Wikipedia

    en.wikipedia.org/wiki/Valve_of_inferior_vena_cava

    When the pressure in the left atrium exceeds the pressure in the right atrium, the foramen ovale begins to close and limits the blood flow between the left and right atrium. While the eustachian valve persists in adult life, it essentially does not have a specific function after the gestational period.

  8. Septum secundum - Wikipedia

    en.wikipedia.org/wiki/Septum_secundum

    Before birth, it does not fuse with the septum intermedium, leaving a gap to form the foramen ovale. [1] Shortly after birth, it fuses with the septum primum to form the interatrial septum, and the foramen ovale is closed. [1] The fossa ovalis denotes the free margin of the septum secundum after birth.

  9. Foramen secundum - Wikipedia

    en.wikipedia.org/wiki/Foramen_secundum

    Once a baby is born, blood should flow through the lungs, which now function to provide oxygen to the blood. The foramen secundum and foramen ovale act as a shunt where blood bypasses the lungs and does not become oxygenated. To provide proper blood flow as a newborn, the foramen secundum and foramen ovale must close at birth.