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A rough-skinned newt underwater A rough-skinned newt at Brice Creek in Oregon. Throughout much of the newt's range, the common garter snake (Thamnophis sirtalis) has been observed to exhibit resistance to the tetrodotoxin produced in the newt's skin. While in principle the toxin binds to a tube-shaped protein that acts as a sodium channel in ...
Tylototriton shanjing, the emperor newt, Mandarin newt or Mandarin salamander, is a highly toxic newt native to Yunnan and parts of South China. It is sometimes seen in private collections, and is sometimes available for sale at certain reptile and amphibian-specializing pet stores and occasionally through captive breeders .
There are several causes of toxic optic neuropathy. [1] Among these are: ingestion of methanol (wood alcohol), ethylene glycol (automotive antifreeze), disulfiram (used to treat chronic alcoholism), halogenated hydroquinolones (amebicidal medications), ethambutol and isoniazid (tuberculosis treatment), and antibiotics such as linezolid and chloramphenicol as well as chloroquine and the related ...
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
Alimentary toxic aleukia is a mycotoxin-induced condition characterized by nausea, vomiting, diarrhea, leukopenia (aleukia), hemorrhaging, skin inflammation, and sometimes death. [1] Alimentary toxic aleukia almost always refers to the human condition associated with presence of T-2 Toxin .
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
The Coastal Range newt produce a potent poison called tetrodotoxin from specialized glands in their skin. Ingestion of this poison by handling or eating them causes severe neurological symptoms and, in some instances, death from respiratory or cardiac failure. The toxin found in juveniles is several times more potent than that in adults.
Amnesic shellfish poisoning (ASP) is an illness caused by consumption of shellfish that contain the marine biotoxin called domoic acid. [1] In mammals , including humans, domoic acid acts as a neurotoxin , causing permanent short-term memory loss , brain damage , and death in severe cases.