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Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2] This leads to a rigid, sickle -like shape under ...
The National Heart, Lung, and Blood Institute (NHLBI) is the third largest Institute of the National Institutes of Health, located in Bethesda, Maryland, United States.It is tasked with allocating about $3.6 billion in FY 2020 [1] in tax revenue to advancing the understanding of the following issues: development and progression of disease, diagnosis of disease, treatment of disease, disease ...
Shurin has been active in clinical research in many aspects of pediatric hematology-oncology, including participation in the Children's Cancer Group (CCG), now the Children's Oncology Group, as well as multiple studies of sickle cell disease and hemostasis. She also served on the Executive Committee of the CCG and founded and chaired the CCG ...
December 8, 2023 at 1:19 PM. The Food and Drug Administration on Friday approved a powerful treatment for sickle cell disease, a devastating illness that affects more than 100,000 Americans, the ...
Julie Ann Panepinto is an American pediatric hematologist-oncologist and physician-scientist. She specializes in health outcomes research and sickle cell disease. Panepinto became the acting director of the division of blood diseases and resources at the National Heart, Lung, and Blood Institute in 2022. She was a professor of pediatrics and ...
Hematology. Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous). Those who are heterozygous for the sickle cell allele produce both ...
Odame's research and clinical works are in the field of sickle cell disease, thalassemia and other hematological disorders.His work at the Centre for Global Child Health also focuses on creating a continuous partnership between clinicians and scientists globally to foster academic research and improve medical care especially in developing countries with the largest disease burden.
Childhood cancer is cancer in a child. About 80% of childhood cancer cases in high-income countries can be successfully treated via modern medical treatments and optimal patient care. [2][3] However, only about 10% of children diagnosed with cancer reside in high-income countries where the necessary treatments and care is available. [4][5 ...