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  2. Genetic transformation - Wikipedia

    en.wikipedia.org/wiki/Genetic_transformation

    This process of the second bacterial cell taking up new genetic material is called transformation. In molecular biology and genetics, transformation is the genetic alteration of a cell resulting from the direct uptake and incorporation of exogenous genetic material from its surroundings through the cell membrane(s).

  3. Oncogene - Wikipedia

    en.wikipedia.org/wiki/Oncogene

    An oncogene is a gene that has the potential to cause cancer. [1] In tumor cells, these genes are often mutated, or expressed at high levels. [2] Most normal cells undergo a preprogrammed rapid cell death if critical functions are altered and then malfunction.

  4. Mobile genetic elements - Wikipedia

    en.wikipedia.org/wiki/Mobile_genetic_elements

    These mobile genetic elements do not have a protective protein coating. Specifically, these mobile genetic elements are found in angiosperms. [20] [21] [26] Endogenous viral element: These are viral nucleic acids integrated into the genome of a cell. They can move and replicate multiple times in the host cell without causing disease or mutation.

  5. Gene delivery - Wikipedia

    en.wikipedia.org/wiki/Gene_delivery

    Gene delivery is the process of introducing foreign genetic material, such as DNA or RNA, into host cells. [1] Gene delivery must reach the genome of the host cell to induce gene expression . [ 2 ] Successful gene delivery requires the foreign gene delivery to remain stable within the host cell and can either integrate into the genome or ...

  6. Viral transformation - Wikipedia

    en.wikipedia.org/wiki/Viral_transformation

    Cells with transforming infections undergo immortalization and inherit the genetic material to produce tumors. Since the term cytocidal, or cytolytic, refers to cell death, these three infections are not mutually exclusive. Many transforming infections by DNA tumor viruses are also cytocidal. [1] Table 1: Cellular effects of viral infections [1]

  7. Methyltransferase - Wikipedia

    en.wikipedia.org/wiki/Methyltransferase

    It directly impacts chromatin structure and can modulate gene transcription, or even completely silence or activate genes, without mutation to the gene itself. Though the mechanisms of this genetic control are complex, hypo- and hypermethylation of DNA is implicated in many diseases.

  8. Genetic engineering techniques - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering_techniques

    Bacterial transformation involves moving a gene from one bacteria to another. It is integrated into the recipients plasmid. and can then be expressed by the new host. Transformation is the direct alteration of a cell's genetic components by passing the genetic material through the cell membrane.

  9. Transgene - Wikipedia

    en.wikipedia.org/wiki/Transgene

    There is a potential to use human gene therapy to replace a mutated gene with an unmutated copy of a transgene in order to treat the genetic disorder. This can be done through the use of Cre-Lox or knockout. Moreover, genetic disorders are being studied through the use of transgenic mice, pigs, rabbits, and rats.