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The exact mechanism of transport is not known; however, findings indicate that ATP binding to TAP-1 is the initial step in the transport process, and that ATP bound to TAP-1 induces ATP binding in TAP-2. It has also been shown that undocking of the loaded MHC class I is linked to the transport cycle of TAP caused by signals from the TAP-1 subunit.
Transporter associated with antigen processing 1 (TAP1) is a protein that in humans is encoded by the TAP1 gene. A member of the ATP-binding cassette transporter family, it is also known as ABCB2. [ 5 ] [ 6 ]
Obg-like ATPase 1 is an enzyme that in humans is encoded by the OLA1 gene. [ 5 ] [ 6 ] Ola1 belongs to the protein family of Obg-like GTPases but defines an exceptional example of a protein that has evolved altered nucleotide specificity and binds adenosine triphosphate (ATP) with higher affinity than guanosine triphosphate (GTP).
Our Husband Has Gone Mad Again is a play by Olawale Gladstone Emmanuel Rotimi, best known as Ola Rotimi. The play centers around the entry of a former military Major, Lejoka-Brown, into politics in contemporary Africa. [1] [2]
Created Date: 8/30/2012 4:52:52 PM
The size of the Ghouta has varied considerably at different times and according to different surveys and estimates. In the 20th century, the Syrian journalist Muhammad Kurd Ali approximated that it spanned an area 20 by 10 kilometers (12.4 mi × 6.2 mi), [5] while a 2000 a survey reported that the region spanned 19,000 hectares. [6]
Grip Am is a play by Olawale Gladstone Emmanuel Rotimi, best known as Ola Rotimi, a playwright and theatre director. The play centers around Isa, a poor farmer who has many challenges in his life alongside a difficult marriage. [1] [2]
Since its invention by Dr. John T. Gleaves (then at Monsanto Company) in late 1980s, [1] TAP has been used to study a variety of industrially and academically relevant catalytic reactions, bridging the gap between surface science experiments and applied catalysis. [2] The state-of-the-art TAP installations (TAP-3) do not only provide better ...