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The cerebellum ("little brain") is a structure located at the rear of the brain, near the spinal cord. It looks like a miniature version of the cerebral cortex, in that it has a wavy, or convoluted surface. [3]
Learning about the dementia stages can help caregivers track and monitor stage-related symptoms to identify a loved one’s brain-health status. The seven stages of dementia include: Stage 1: No ...
The hallmark symptom of LATE is a progressive memory loss that predominantly affects short-term and episodic memory. [1] This impairment is often severe enough to interfere with daily functioning and usually remains the chief neurologic deficit, unlike other types of dementia in which non-memory cognitive domains and behavioral changes might be noted earlier or more prominently. [1]
The symptoms will progress from mild cognitive problems, such as memory loss through increasing stages of cognitive and non-cognitive disturbances, eliminating any possibility of independent living, especially in the late stages of the disease. [41] Life expectancy of people with AD is reduced. [227]
The impact on life expectancy depends on the individual condition, [9] but is usually severe without treatment. [1] [3] It's estimated only 25–29% of people affected survive to adulthood, and only 10% to the age of 50. [1] The median life expectancy is around 9 years, and the average life expectancy is 16.3 years. [1]
Since life extension is only pertinent if accompanied by health span extension, and, more importantly, by preserving brain health and cognition, finding rejuvenating approaches that act simultaneously in peripheral tissues and in brain function is a key strategy for development of rejuvenating technology.
The symptoms of this dementia depend on where in the brain the strokes occurred and whether the blood vessels affected were large or small. [13] Repeated injury can cause progressive dementia over time, while a single injury located in an area critical for cognition such as the hippocampus, or thalamus, can lead to sudden cognitive decline. [75]
Age-related memory loss, sometimes described as "normal aging" (also spelled "ageing" in British English), is qualitatively different from memory loss associated with types of dementia such as Alzheimer's disease, and is believed to have a different brain mechanism.