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Stiff-person syndrome (SPS), also known as stiff-man syndrome, [1] is a rare neurological disorder of unclear cause characterized by progressive muscular rigidity and stiffness. The stiffness primarily affects the truncal muscles and is characterised by spasms , resulting in postural deformities.
Immunoglobulin therapy is also used in some treatment protocols for secondary immunodeficiencies such as human immunodeficiency virus (HIV), some autoimmune disorders (such as immune thrombocytopenia and Kawasaki disease), some neurological diseases (multifocal motor neuropathy, stiff person syndrome, multiple sclerosis and myasthenia gravis ...
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Stiff-person syndrome — often called SPS — is a rare autoimmune disorder, meaning that infection-fighting cells in the body mistakenly attack healthy tissues.
The National Institute of Neurological Disorders and Stroke (NINDS) defines SPS as a progressive disorder, characterised by “stiff muscles in the trunk (torso), arms, and legs; and greater ...
Morvan's syndrome is a rare, life-threatening autoimmune disease named after the nineteenth century French physician Augustin Marie Morvan. "La chorée fibrillaire" was first coined by Morvan in 1890 when describing patients with multiple, irregular contractions of the long muscles , cramping , weakness, pruritus , hyperhidrosis , insomnia and ...