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The integumentary system includes skin, hair, scales, feathers, hooves, claws, and nails. It has a variety of additional functions: it may serve to maintain water balance, protect the deeper tissues, excrete wastes, and regulate body temperature , and is the attachment site for sensory receptors which detect pain, sensation, pressure, and ...
Keratin protein expression within the various layers and anatomic locations of the human integumentary system Keratin type Location of expression 1: Suprabasal epidermis of skin 2 (2e) Granular layer: 3: Cornea: 4: Suprabasal epidermis of mucosa 5: Basal layer: 6a: Suprabasal palmoplantar skin 6b: Basal palmoplantar skin Nail bed Hair follicle ...
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermal layer provides a barrier to infection from environmental pathogens [ 2 ] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss .
The epidermis, "epi" coming from the Greek language meaning "over" or "upon", is the outermost layer of the skin. It forms the waterproof, protective wrap over the body's surface, which also serves as a barrier to infection and is made up of stratified squamous epithelium with an underlying basal lamina.
Histologic image showing a section of epidermis. Stratum basale labeled near bottom. The stratum basale (basal layer, sometimes referred to as stratum germinativum) is the deepest layer of the five layers of the epidermis, the external covering of skin in mammals. The stratum basale is a single layer of columnar or cuboidal basal cells.
The epidermis is the most ... Conditions of the human integumentary system ... [17] [18] Therefore, most current textbooks present a classification based on location ...
Merkel cell. Merkel cells are found in the skin and some parts of the mucosa of all vertebrates. In mammalian skin, they are clear cells found in the stratum basale [2] [3] (at the bottom of sweat duct ridges) of the epidermis approximately 10 μm in diameter.
Within the healed epidermis they will be replaced by keratinocytes originating from the epidermis. [29] [30] At the opposite, epidermal keratinocytes, can contribute to de novo hair follicle formation during the healing of large wounds. [31] Functional keratinocytes are needed for tympanic perforation healing. [32]