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Doxycycline is a broad-spectrum antibiotic of the tetracycline class used in the treatment of infections caused by bacteria and certain parasites. [1] It is used to treat bacterial pneumonia, acne, chlamydia infections, Lyme disease, cholera, typhus, and syphilis. [1]
Dicloxacillin is a narrow-spectrum β-lactam antibiotic of the penicillin class. [1] It is used to treat infections caused by susceptible (non-resistant) Gram-positive bacteria . [ 1 ] It is active against beta-lactamase -producing organisms such as Staphylococcus aureus , which would otherwise be resistant to most penicillins .
Alternatively, tetracyclines (eg, doxycycline), and respiratory fluoroquinolones (eg, levofloxacin or moxifloxacin) can be used; they have an undesirable side effect profile in children. Beta-lactams such as penicillin are completely ineffective, because they target the cell wall synthesis. [citation needed]
Antibiotic use is also associated with side effects such as nausea, diarrhea, dizziness, taste distortion, or headaches. [120] In the UK, treatment before culture results with amoxicillin is recommended as the first line for community-acquired pneumonia, with doxycycline or clarithromycin as alternatives. [69]
Depending on the type of pneumonia, it may include an antibiotic, antiviral, or antifungal medication. If the pneumonia is severe, IV antibiotics and oxygen, administered in a hospital setting ...
Adverse effects to monobactams can include skin rash and occasional abnormal liver functions. [citation needed]Monobactam antibiotics exhibit no IgE cross-reactivity reactions with penicillin but have shown some cross reactivity with cephalosporins, most notably ceftazidime, which contains an identical side chain as aztreonam. [8]