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The PB1 gene codes for the PB1 protein and the PB1-F2 protein. The PB1-F2 protein probably contributes to viral pathogenicity and might have an important role in determining the severity of pandemic influenza. Until H5N1, all known avian influenza viruses had a Glu at position 627, while all human influenza viruses had a lysine.
From this point on, avian influenza experts increasingly refer to containment as a strategy that can delay but not prevent a future avian flu pandemic. [citation needed] Variants have been found in a number of domestic cats, leopards, and tigers in Thailand, with high lethality. [18] "The Thailand Zoo tiger outbreak killed more than 140 tigers ...
Avian influenza, also known as avian flu or bird flu, is a disease caused by the influenza A virus, which primarily affects birds but can sometimes affect mammals including humans. [1] Wild aquatic birds are the primary host of the influenza A virus, which is enzootic (continually present) in many bird populations.
Influenza A virus subtype H5N1 (A/H5N1) is a subtype of the influenza A virus, which causes the disease avian influenza (often referred to as "bird flu"). It is enzootic (maintained in the population) in many bird populations, and also panzootic (affecting animals of many species over a wide area). [ 1 ]
China announced a fresh outbreak of bird flu, saying 2,600 birds have died from the disease in Inner Mongolia. The deaths, at a farm near the region's capital of Hohhot, were due to the H5N1 strain, the Xinhua news agency said. Locations of 2005 outbreaks in Croatia. October 26, 2005 Croatia announced H5N1 strain was found in dead swans. [14] [15]
This is a timeline of influenza, briefly describing major events such as outbreaks, epidemics, pandemics, discoveries and developments of vaccines.In addition to specific year/period-related events, there is the seasonal flu that kills between 250,000 and 500,000 people every year and has claimed between 340 million and 1 billion human lives throughout history.
H5N1 bird-flu strain had been found in tens of thousands of poultry in Israel. [55] March 18, 2006 Egypt has confirmed the first human death caused by H5N1 virus. [56] March 19, 2006 Egypt has reported its second human case of bird flu, a 30-year-old man who worked on a chicken farm in the province of Qalyoubiya. [57] March 20, 2006
On November 7, the CDC reported asymptomatic bird flu infection in 4 workers at dairy farms. The workers didn't recall ever being sick but had antibodies showing that they had been infected with bird flu. [98] On November 22, the CDC confirmed the first case of bird flu in a U.S. child, being the 55th case of bird flu in humans in the U.S.