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A gonad, sex gland, or reproductive gland [1] is a mixed gland and sex organ that produces the gametes and sex hormones of an organism. Female reproductive cells are egg cells, and male reproductive cells are sperm. [2] The male gonad, the testicle, produces sperm in the form of spermatozoa. The female gonad, the ovary, produces egg cells
Sexual differentiation is the process of development of the sex differences between males and females from an undifferentiated zygote. [1] [2] Sex determination is often distinct from sex differentiation; sex determination is the designation for the development stage towards either male or female, while sex differentiation is the pathway towards the development of the phenotype.
The gonadal ridge, in turn, develops into a gonad. This is a testis in the male and an ovary in the female. At first, the mesonephros and gonadal ridge are continuous, but as the embryo grows the gonadal ridge gradually becomes pinched off from the mesonephros. However, some cells of mesonephric origin join the gonadal ridge.
Genes associated with the developing gonad can be categorized into those that form the sexually indifferent gonad, those that determine whether the indifferent gonad will differentiate as male or female, and those that promote differentiation into male or female parts. Genes that form the sexually indifferent gonad are SF1 and WT1.
This list of related male and female reproductive organs shows how the male and female reproductive organs and the development of the reproductive system are related, sharing a common developmental path. This makes them biological homologues. These organs differentiate into the respective sex organs in males and females.
Male gonad (testes, left) and female gonad (ovaries, right) Males have two testicles of similar size contained within the scrotum, which is an extension of the abdominal wall. [1] Scrotal asymmetry, in which one testicle extends farther down into the scrotum than the other, is common. This is because of the differences in the vasculature's ...
In both plants and animals, gamete size difference is the fundamental difference between females and males. [2] Anisogamy most likely evolved from isogamy. [3] Since the biological definition of male and female is based on gamete size, the evolution of anisogamy is viewed as the evolutionary origin of male and female sexes.
Phenotypic differences between sexes are evident even in cultured cells from tissues. [132] For example, female muscle-derived stem cells have a better muscle regeneration efficiency than male ones. [133] There are reports of several metabolic differences between male and female cells [134] and they also respond to stress differently. [135]