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Codon usage bias in Physcomitrella patens. Codon usage bias refers to differences in the frequency of occurrence of synonymous codons in coding DNA.A codon is a series of three nucleotides (a triplet) that encodes a specific amino acid residue in a polypeptide chain or for the termination of translation (stop codons).
The Codon Adaptation Index (CAI) [1] is the most widespread technique for analyzing codon usage bias.As opposed to other measures of codon usage bias, such as the 'effective number of codons' (Nc), which measure deviation from a uniform bias (null hypothesis), CAI measures the deviation of a given protein coding gene sequence with respect to a reference set of genes.
Also, as extensive libraries are provided with the package, it is a platform to allow other scientists to develop and release software in true open source spirit. EMBOSS also integrates a range of currently available packages and tools for sequence analysis into a seamless whole. EMBOSS is an acronym for European Molecular Biology Open Software ...
Other export options include the current timetree calibrations, analysis summary, partition list, and pairwise distances. [40] The tree explorer also provide options to save the current tree display in an image format or to the clipboard under the image menu option. The image format supported are BMP, PNG, PDF, SVG, TIFF, and EMF. [41]
Effective number of codons (abbreviated as ENC or Nc) is a measure to study the state of codon usage biases in genes and genomes. [1] The way that ENC is computed has obvious similarities to the computation of effective population size in population genetics . [ 2 ]
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This table is found in both DNA Codon Table and Genetic Code (And probably a few other places), so I'm pulling it out so it can be common. By default it's the DNA code (using the letter T for Thymine); use template parameter "T=U" to make it the RNA code (using U for Uracil). See also Template:Inverse codon table
FASDA (Fast And Simple Differential Analysis) is a fast and memory-efficient differential analysis tool written in C, following object-oriented design and strict code-quality practices. It takes SAM/BAM/CRAM or kallisto abundance files directly as input, and produces fold-changes and exact P-values for up to 5 replicates, near-exact P-values ...