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Originally available only by prescription, it was approved by the FDA for over-the-counter sale in February 2007. [32] In May 2010, the U.S. Food and Drug Administration (FDA) approved a revised label for Xenical to include new safety information about rare cases of severe liver injury that have been reported with the use of this medication. [33]
The Food and Drug Administration (FDA) of the Philippines, formerly the Bureau of Food and Drugs (BFAD / ˈ b iː f æ d /; 1982–2009), is a health regulatory agency under the Department of Health created on 1963 by Republic Act No. 3720, amended on 1987 by Executive Order 175 otherwise known as the "Food, Drugs and Devices, and Cosmetics Act", and subsequently reorganized by Republic Act No ...
On 23 January 2006, an FDA advisory panel voted 11 to 3 to recommend the approval of an OTC formulation of orlistat, to be sold under the brand name Alli by GlaxoSmithKline. [41] Approval was granted on 7 February 2007, [ 42 ] and Alli became the first weight loss drug officially sanctioned by the U.S. government for over-the-counter use. [ 43 ]
In 1959, phentermine first received approval from the US Food and Drug Administration (FDA) as an appetite suppressant. [43] Eventually a hydrochloride salt and a resin form became available. [43] Phentermine was marketed with fenfluramine or dexfenfluramine as a combination appetite suppressant and fat burning agent under the popular name fen ...
It was approved by the U.S. Food and Drug Administration (FDA) in November 1997 [24] for the treatment of obesity. Sibutramine is reported to be a prodrug to two active metabolites , desmethylsibutramine (M1; BTS-54354) and didesmethylsibutramine (M2; BTS-54505), with much greater potency as monoamine reuptake inhibitors.
Mitragyna speciosa is a tropical evergreen tree of the Rubiaceae family (coffee family) native to Southeast Asia. [3] It is indigenous to Cambodia, Thailand, Indonesia, Malaysia, Myanmar, and Papua New Guinea, [4] where its leaves, known as kratom, have been used in herbal medicine since at least the 19th century. [5]