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Encephalitis lethargica is an atypical form of encephalitis. Also known as " sleeping sickness " or " sleepy sickness " (distinct from tsetse fly –transmitted sleeping sickness ), it was first described in 1917 by neurologist Constantin von Economo [ 2 ] [ 3 ] and pathologist Jean-René Cruchet . [ 4 ]
One of the first instances in which an infectious disease was associated with klazomania was the notable pandemic of the encephalitis lethargica from 1916 to 1927. [1] This pandemic also gave rise to observations of other tics that came to be associated with encephalitis lethargica such as complex vocalizations of blocking, echolalia, palilalia ...
Encephalitis lethargica is a neurological syndrome that causes lethargy, a “mask like” face, excessive blood in the meninges, and other general neurological symptoms. [5] Officially recognized as its own condition in 1917, it is believed to have existed far longer in human history. [ 5 ]
Historically, starting in 1917 an epidemic of encephalitis lethargica, also called von Economo's encephalitis or "sleepy-disease" occurred, possibly related to the 1918 Spanish flu pandemic; however, even with the use of modern molecular diagnostic tests on appropriate corpses, no firm link between encephalitis lethargica and influenza has been ...
Encephalitis with meningitis is known as meningoencephalitis, while encephalitis with involvement of the spinal cord is known as encephalomyelitis. [ 2 ] The word is from Ancient Greek ἐγκέφαλος , enképhalos 'brain', [ 37 ] composed of ἐν , en , 'in' and κεφαλή , kephalé , 'head', and the medical suffix -itis 'inflammation'.
In 1969, Dr. Malcolm Sayer is a dedicated and caring physician at a local hospital in the New York City borough of the Bronx.After working extensively with the catatonic patients who survived the 1919–1930 epidemic of encephalitis lethargica, Sayer discovers that certain stimuli will reach beyond the patients' respective catatonic states.
Oliver Wolf Sacks (9 July 1933 – 30 August 2015) was a British neurologist, naturalist, historian of science, and writer. [2] Born in London, Sacks received his medical degree in 1958 from The Queen's College, Oxford, before moving to the United States, where he spent most of his career.
Eastern equine encephalitis, Japanese encephalitis, Venezuelan equine encephalitis, and Western equine encephalitis: a group of viral illnesses that can affect horses and humans; collectively termed Equine encephalitis. Experimental autoimmune encephalomyelitis (EAE), an animal model of brain inflammation.