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  2. Glycine encephalopathy - Wikipedia

    en.wikipedia.org/wiki/Glycine_encephalopathy

    Glycine encephalopathy is a rare autosomal recessive disorder of glycine metabolism. After phenylketonuria, glycine encephalopathy is the second most common disorder of amino acid metabolism. The disease is caused by defects in the glycine cleavage system, an enzyme responsible for glycine catabolism. There are several forms of the disease ...

  3. High-dose chemotherapy - Wikipedia

    en.wikipedia.org/wiki/High-dose_chemotherapy

    A research conducted by Einhorn and team demonstrated the effectiveness of high dose chemotherapy in this scenario revealing remissions even in patients, with refractory disease. [7] Some breast cancer patients, particularly those with high-risk features such as a large number of involved lymph nodes, aggressive tumor biology, or those who do ...

  4. High-grade serous carcinoma - Wikipedia

    en.wikipedia.org/wiki/High-grade_serous_carcinoma

    Since 1975, survival rates for ovarian cancer have steadily improved with a mean decrease of 51% by 2006 of risk of death from ovarian cancer for an advanced stage tumour. [58] The increase has mainly been due to successful extended life expectancy of affected patients rather than an improvement in cure rates.

  5. Hepatic veno-occlusive disease - Wikipedia

    en.wikipedia.org/wiki/Hepatic_veno-occlusive_disease

    Hepatic veno-occlusive disease (VOD) or veno-occlusive disease with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant or excessive exposure to hepatotoxic pyrrolizidine alkaloids .

  6. NMDA receptor modulator - Wikipedia

    en.wikipedia.org/wiki/NMDA_receptor_modulator

    From there, it was hypothesized that people with psychosis from schizophrenia would benefit from increased glutamate transmission and glycine was added with strong recovery rates noted especially in the area of negative and cognitive symptoms. Glycine, however, sporadic results aside (dose 60 g/day or 0.8 g/kg, [2] [3] approximately the amount ...

  7. Chronic lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

    Because of the prolonged survival, which was typically about 10 years in past decades, but which can extend to a normal life expectancy, the prevalence (number of people living with the disease) is much higher than the incidence (new diagnoses). [2] CLL is the most common type of leukemia in the UK, accounting for 38% of all leukemia cases.