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Hepatic microvascular dysplasia (HMD or MVD) or portal atresia is a disorder where mixing of venous blood and arterial blood in the liver occurs at the microscopic level. It occurs most commonly in certain dog breeds such as the Cairn and Yorkshire terriers although any dog breed may be at risk. [1] [2] [3] This disease may also be found in cats.
All forms of portosystemic shunts produce various neurological, gastrointestinal, and urinary symptoms. [3]Symptoms of congenital PSS usually appear by six months of age [4] and include failure to gain weight, vomiting, and signs of hepatic encephalopathy (a condition where toxins normally removed by the liver accumulate in the blood and impair the function of brain cells) such as seizures ...
A portosystemic shunt or portasystemic shunt (medical subject heading term; PSS), also known as a liver shunt, is a bypass of the liver by the body's circulatory system.It can be either a congenital (present at birth) or acquired condition and occurs in humans as well as in other species of animals.
Current cure rates using stem cell therapy in dogs approximates that achieved in humans, 40-50%. When cost is a factor, prednisone used alone can improve the symptoms dramatically, but it does not significantly affect the survival rate. The average survival times of dogs treated with prednisone and untreated dogs are both one to two months. [1]
Many of the affected dogs showed abnormal liver function which resulted in much of the early focus implicating hepatic disorders as the cause of the newly discovered disease. However, after the number of symptomatic dogs with apparently normal livers increased, the concentration shifted to diet in early 1999, as through thorough investigation ...
Hypertrophic Osteodystrophy (HOD) is a bone disease that occurs most often in fast-growing large and giant breed dogs; however, it also affects medium breed animals like the Australian Shepherd. The disorder is sometimes referred to as metaphyseal osteopathy , and typically first presents between the ages of 2 and 7 months. [ 1 ]
Hypoadrenocorticism in dogs, or, as it is known in people, Addison's disease, is an endocrine system disorder that occurs when the adrenal glands fail to produce enough hormones for normal function. The adrenal glands secrete glucocorticoids such as cortisol [ 1 ] and mineralocorticoids such as aldosterone ; [ 2 ] when proper amounts of these ...
Canine mastadenovirus A also causes disease in wolves, coyotes, and bears, and encephalitis in foxes. [1] The virus is spread in the feces, urine, blood, saliva, and nasal discharge of infected dogs. It is contracted through the mouth or nose, where it replicates in the tonsils. The virus then infects the liver and kidneys.