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Clindamycin has been proven to decrease the risk of premature births in women diagnosed with bacterial vaginosis during early pregnancy to about a third of the risk of untreated women. [ 39 ] The combination of clindamycin and quinine is the standard treatment for severe babesiosis .
It contains clindamycin, as the phosphate, a lincosamide antibacterial; adapalene, a synthetic retinoid; and benzoyl peroxide, an oxidizing agent. [2] It is applied to the skin . [ 2 ]
However, these classifications are based on laboratory behavior. The development of antibiotics has had a profound effect on the health of people for many years. Also, both people and animals have used antibiotics to treat infections and diseases. In practice, both treat bacterial infections. [1]
WHO recommends taking supplements of 30–60 mg of elemental iron a day throughout pregnancy for all pregnant individuals. Iron demand depends on individual specific factors and risk of deficiency; for specific dose recommendations, individuals should discuss with their doctors. [65]
Clindamycin/benzoyl peroxide, sold under the brand name Benzaclin among others, is a topical gel used for the treatment of acne. [7] It is a fixed-dose combination of clindamycin , as the phosphate, an antibiotic ; and benzoyl peroxide , an antiseptic .
Out of the many families of multidrug resistance pumps, lincosamides are most commonly shunted through pumps belonging to the resistance-nodulation-cell division superfamily. [17] Staphylococci express efflux pumps with specificity for 14 and 15 member ring macrolides and streptogramin B, but not lincosamide molecules.
GBS-EOD manifests from 0 to 7 living days in the newborn, with most of the cases of EOD being apparent within 24 h from birth. GBS-LOD starts between 7 and 90 days after birth. [ 4 ] [ 12 ] [ 14 ] [ 22 ] Roughly 50% of newborns of GBS-colonized mothers are also GBS-colonized and (without prevention measures) 1-2% of these newborns will develop ...
The WHO recommends avoiding ACT for women in their first trimester of pregnancy due to a lack of research on artemisinin's safety in early pregnancy. Instead the WHO recommends a seven-day course of clindamycin and quinine. [15] For pregnant women in their second or third trimesters, the WHO recommends a normal treatment course with an ACT. [16]