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The drug's mode of action is not exactly known at present, but experimental evidence indicates praziquantel increases the permeability of the membranes of schistosome cells towards calcium ions. The drug thereby induces contraction of the parasites' muscle, resulting in paralysis in the contracted state.
It is less effective as a sedative if the horse is already excited. [23] Additionally, acepromazine is used as a vasodilator in the treatment of laminitis, where an oral dose equivalent to "mild sedation" is commonly used, although the dose used is highly dependent on the treating veterinarian. While it is shown to elicit vasodilation in the ...
pentoxyfylline – xanthine derivative used in as an antiinflammatory drug and in the prevention of endotoxemia; pergolide – dopamine receptor agonist used for the treatment of pituitary pars intermedia dysfunction in horses; phenobarbital – anti-convulsant used for seizures; phenylbutazone – nonsteroidal anti-inflammatory drug (NSAID)
A horse may be returned to work if symptoms have ceased and is no longer on NSAIDs or other prescribed drugs related to treatment of ER, this can otherwise can hide signs of another bout of ER. If NSAIDs or other treatment drugs are needed to keep the horse comfortable, or if the horse is reluctant to continue work, the animal is not yet ready ...
References A ace Slang for the drug acepromazine or acetyl promazine (trade names Atravet or Acezine), which is a sedative : 3 commonly used on horses during veterinary treatment, but also illegal in the show ring. Also abbreviated ACP. action The way a horse elevates its legs, knees, hock, and feet. : 3 Also includes how the horse uses its shoulder, humerus, elbow, and stifle; most often used ...
Mohler, John R., Dourine of horses – its cause and suppression (1911) Covering sickness, or dourine (French, from the Arabic darina, meaning mangy (said of a female camel), feminine of darin, meaning dirty), [1] is a disease of horses and other members of the family Equidae.
Pharmacotherapy, also known as pharmacological therapy or drug therapy, is defined as medical treatment that utilizes one or more pharmaceutical drugs to improve ongoing symptoms (symptomatic relief), treat the underlying condition, or act as a prevention for other diseases (prophylaxis).
Equine drug testing is a form of drug testing applied to performance horses in regulated competition. Most common in racehorses , drug tests are also performed on horses in endurance riding and in international competition such as the Olympics and FEI -sanctioned competition.