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The recommended dosage for suppression therapy for recurrent outbreaks is 1,000 mg of valacyclovir once a day or 400 mg Acyclovir taken twice a day. In addition to preventing outbreaks, these medications greatly reduce the chance of infecting someone while the patient is not having an outbreak. [citation needed]
The drug is predominantly active against HSV and, to a lesser extent, VZV. It is only of limited efficacy against EBV and CMV. However, valaciclovir has been shown to lower or eliminate the presence of the Epstein–Barr virus in subjects afflicted with acute mononucleosis, leading to a significant decrease in the severity of symptoms.
Onset is typically around 4 days after exposure with symptoms lasting up to 4 weeks. [1] Once infected further outbreaks may occur but are generally milder. [1] The disease is typically spread by direct genital contact with the skin surface or secretions of someone who is infected. [1] This may occur during sex, including anal, oral, and manual ...
An immunity to the virus is built over time. Most infected individuals experience fewer outbreaks and outbreak symptoms often become less severe. After several years, some people become perpetually asymptomatic and no longer experience outbreaks, though they may still be contagious to others. Immunocompromised individuals may experience longer ...
A zinc oxide, anesthetic, or antiviral cream appears to decrease the duration of symptoms by a small amount. [1] Antiviral medications may also decrease the frequency of outbreaks. [1] [7] About 2.5 per 1000 people are affected with outbreaks in any given year. [1] After one episode about 33% of people develop subsequent episodes. [1]
The new "FLiRT" COVID-19 variants, including KP.3 and KP.2, are spreading in the United States. Will there be a summer surge? Experts discuss transmission, symptoms, and vaccines.