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The specialized olfactory receptor neurons of the olfactory nerve are located in the olfactory mucosa of the upper parts of the nasal cavity.The olfactory nerves consist of a collection of many sensory nerve fibers that extend from the olfactory epithelium to the olfactory bulb, passing through the many openings of the cribriform plate, a sieve-like structure of the ethmoid bone.
Each glomerulus is composed of two compartments, the olfactory nerve zone and the non-olfactory nerve zone. The olfactory nerve zone is composed of preterminals and terminals of the olfactory nerve and is where the olfactory receptor cells make synapses on their targets. [2] The non-olfactory nerve zone is composed of the dendritic processes of ...
The peripheral olfactory system consists mainly of the nostrils, ethmoid bone, nasal cavity, and the olfactory epithelium (layers of thin tissue covered in mucus that line the nasal cavity). The primary components of the layers of epithelial tissue are the mucous membranes, olfactory glands, olfactory neurons, and nerve fibers of the olfactory ...
The axons of OSNs expressing the same odorant receptors converge onto the same glomerulus at the olfactory bulb, allowing for the organization of olfactory information. An olfactory receptor neuron (ORN), also called an olfactory sensory neuron (OSN), is a sensory neuron within the olfactory system .
Olfactory neurons utilize a feedback system from the levels of Ca 2+ ions to activate its adaptation to prolonged smells. Due to the fact that the olfactory signal transduction uses a second messenger transduction system, the mechanism of adaptation includes several factors that mostly include CaMK or calmodulin bound to Ca 2+ ions.
Unique to the olfactory and gustatory systems, at least in mammals, is the implementation of both peripheral and central mechanisms of action. [ clarification needed ] The peripheral mechanisms involve olfactory receptor neurons which transduce a chemical signal along the olfactory nerve , which terminates in the olfactory bulb .
A nomenclature system has been devised for the olfactory receptor family [33] and is the basis for the official Human Genome Project symbols for the genes that encode these receptors. The names of individual olfactory receptor family members are in the format "ORnXm" where: OR is the root name (Olfactory Receptor superfamily)
The olfactory mucosa is the neuroepithelial mucosa [1] lining the roof and upper parts of the septum and lateral wall of the nasal cavity [1] [2] which contains bipolar neurons of the primary receptor neurons of the olfactory pathway, as well as supporting cells.