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Kawasaki disease (also known as mucocutaneous lymph node syndrome) is a syndrome of unknown cause that results in a fever and mainly affects children under 5 years of age. [6] It is a form of vasculitis , in which medium-sized blood vessels become inflamed throughout the body. [ 1 ]
Kawasaki disease is most commonly seen in infants and children under five years old and is more likely to affect boys. The disease is self-limited which means that the inflammation will resolve after 6 to 8 weeks but if we left it untreated, there is a 20-25% risk of the heart complications we went over. Alright so let’s look at the symptoms ...
Kawasaki disease is a type of vasculitis where the endothelial cells in the coronary arteries become damaged, potentially leading to complications like myocardial infarction and aneurysms. This video covers the known pathophysiology, important signs and symptoms, diagnostic criteria, and treatment.
Common uses of the Ishikawa diagram are product design and quality defect prevention to identify potential factors causing an overall effect. Each cause or reason for imperfection is a source of variation. Causes are usually grouped into major categories to identify and classify these sources of variation.
Diagnosis of arteritis is based on unusual medical symptoms. [4] Similar symptoms may be caused by a number of other conditions, such as Ehlers-Danlos syndrome and Marfan syndrome (both heritable disorders of connective tissue), tuberculosis, syphilis, spondyloarthropathies, Cogans' syndrome, Buerger's, Behcet's, and Kawasaki disease. [4]
A causal diagram consists of a set of nodes which may or may not be interlinked by arrows. Arrows between nodes denote causal relationships with the arrow pointing from the cause to the effect. There exist several forms of causal diagrams including Ishikawa diagrams, directed acyclic graphs, causal loop diagrams, [10] and why-because graphs (WBGs).
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IFN-α is another product of prolonged SAg exposure. This cytokine is closely linked with induction of autoimmunity, [21] and the autoimmune disease Kawasaki disease is known to be caused by SAg infection. [14] SAg activation in T-cells leads to production of CD40 ligand which activates isotype switching in B cells to IgG and IgM and IgE. [22]