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  2. Periorbital hyperpigmentation - Wikipedia

    en.wikipedia.org/wiki/Periorbital_hyperpigmentation

    Periorbital hyperpigmentation, also known as hereditary dark circles, is characterized by darker skin around the eyes caused by the presence of additional melanin. It is an extremely common hereditary human characteristic and is frequently found on individuals with dark skin. Periorbital hyperpigmentation is most prevalent within the 16–25 ...

  3. Ocular melanosis - Wikipedia

    en.wikipedia.org/wiki/Ocular_melanosis

    Ocular melanosis (OM) is a blue-gray and/or brown lesion of the conjunctiva that can be separated into benign conjunctival epithelial melanosis (BCEM) and primary acquired melanosis (PAM), of which the latter is considered a risk factor for uveal melanoma. [1]

  4. Neurocutaneous melanosis - Wikipedia

    en.wikipedia.org/wiki/Neurocutaneous_melanosis

    The signal due melanin deposits in the leptomeninges typical of neurocutaneous melanosis can be easily detected in MRI scans of patients under four months old. In patients above this age, there is some suggestion that normal brain myelination may partially obscure these signals.

  5. Periorbital dark circles - Wikipedia

    en.wikipedia.org/wiki/Periorbital_dark_circles

    In addition, many skin care ingredients can help in the form of eye creams. Caffeine is a potent vasoconstrictor that has been proven to improve the look of dark circles [16] by constricting, or tightening, the dilated vessels under eyes. Vitamin C can help brighten hyperpigmentation as well as thicken the dermal layer of skin which conceals ...

  6. Heterochromia iridum - Wikipedia

    en.wikipedia.org/wiki/Heterochromia_iridum

    The affected eye may be hyperpigmented (hyperchromic) or hypopigmented (hypochromic). [3] In humans, an increase of melanin production in the eyes indicates hyperplasia of the iris tissues, whereas a lack of melanin indicates hypoplasia. The term is derived from Ancient Greek: ἕτερος, héteros "different" and χρῶμα, chrôma "color ...

  7. Neuromelanin - Wikipedia

    en.wikipedia.org/wiki/Neuromelanin

    Neuromelanin (NM) is a dark pigment found in the brain which is structurally related to melanin. It is a polymer of 5,6-dihydroxyindole monomers. [1] Neuromelanin is found in large quantities in catecholaminergic cells of the substantia nigra pars compacta and locus coeruleus, giving a dark color to the structures. [2]

  8. Pigment dispersion syndrome - Wikipedia

    en.wikipedia.org/wiki/Pigment_dispersion_syndrome

    Pigment dispersion syndrome (PDS) is an eye disorder that can lead to a form of glaucoma known as pigmentary glaucoma.It takes place when pigment cells slough off from the back of the iris and float around in the aqueous humor.

  9. Hyperpigmentation - Wikipedia

    en.wikipedia.org/wiki/Hyperpigmentation

    Many forms of hyperpigmentation are caused by an excess production of melanin. [4] Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such ...