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[43] [failed verification] UVC is the highest-energy, most-dangerous type of ultraviolet radiation, and causes adverse effects that can variously be mutagenic or carcinogenic. [44] Despite the importance of the sun to vitamin D synthesis, it is prudent to limit the exposure of skin to UV radiation from sunlight [45] and from tanning beds. [46]
Ultraviolet radiation is thought to cause up to 95% of basal and squamous cell carcinomas, and between 70-95% of melanomas in people with fair skin. “Skin cancer is caused by exposing the cells ...
The primary cause of skin cancer is prolonged exposure to ultraviolet (UV) radiation from the sun or tanning devices. Skin cancer is the most commonly diagnosed form of cancer in humans. [ 11 ] [ 12 ] [ 13 ] There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma . [ 1 ]
One of the largest promoters of apoptosis is exposure to ultraviolet (UV) light. While UV light is essential to human life it can also cause harm by inducing cancer, immunosuppression, photoaging, inflammation, and cell death. [1] Of the various components of sunlight, ultraviolet radiation B (UVB) (290-320 nm) is considered to be the most harmful.
When evaluating ultraviolet germicidal lights, eye and skin health are primary concerns. UV-B, predominantly responsible for the harmful effects of sunlight, poses the highest risk for erythema, photokeratitis, sunburn and skin cancer. [14] [15] [16] While longer UV-C wavelengths and UV-A can also cause damage, their effects are less severe ...
A radiation burn is a damage to the skin or other biological tissue and organs as an effect of radiation. The radiation types of greatest concern are thermal radiation, radio frequency energy, ultraviolet light and ionizing radiation. The most common type of radiation burn is a sunburn caused by UV radiation.
Ultraviolet radiation is known to suppress the immune system and reduce inflammatory responses. Light therapy for skin conditions like psoriasis usually use 313 nanometer UVB though it may use UVA (315–400 nm wavelength) or a broader spectrum UVB (280–315 nm wavelength). UVA combined with psoralen, a drug taken orally, is known as PUVA ...
The ROS are produced when endogenous photosensitizers are stimulated by UVA radiation. [1] DNA absorption of UV radiation primarily leads to CPD and 6-4 lesions. The neighboring pyrimidines form a cyclobutane pyrimidine dimer in a CPD lesion. DNA absorption of UV radiation can also lead to TC, CC, and TT lesions but with much less frequency.