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The mesonephric duct, also known as the Wolffian duct, archinephric duct, Leydig's duct or nephric duct, is a paired organ that develops in the early stages of embryonic development in humans and other mammals. It is an important structure that plays a critical role in the formation of male reproductive organs.
h. The duct of Müller. i. Its upper, funnel-shaped extremity. k. Its lower end, terminating in the urogenital sinus. l. The genital gland. This vesicle then elongates to form the mesonephric tubule, attaching to the mesonephric duct on one side. Meanwhile, an artery from the dorsal aorta begins extending towards the mesonephric tubule.
m, m. Right and left Müllerian ducts uniting together and running with the Wolffian ducts in gc, the genital cord: m. Müllerian duct, the upper part of which remains as the hydatid of Morgagni; the lower part, represented by a dotted line descending to the prostatic utricle, constitutes the occasionally existing cornu and tube of the uterus ...
As it elongates caudally, the pronephric duct induces nearby intermediate mesoderm in the thoracolumbar area to become epithelial tubules called mesonephric tubules. Each mesonephric tubule receives a blood supply from a branch of the aorta, ending in a capillary tuft analogous to the glomerulus of the definitive nephron. The mesonephric tubule ...
During this time, the single-layered paramesonephric duct epithelium differentiates into other structures, ranging from the ciliated columnar epithelium in the uterine tube to stratified squamous epithelium in the vagina. [8] The paramesonephric ducts and the mesonephric ducts share a majority of the same mesenchyme due to Hox gene expression.
It may contain 10–15 transverse small ducts or tubules that lead to the Gartner's duct (also longitudinal duct of epoophoron) that represents the caudal remnant of the mesonephric ducts and passes through the broad ligament and the lateral wall of the cervix and vagina. The epoophoron is a homologue to the epididymis in the male.
These embryonic structures are the mesonephric ducts (also known as Wolffian ducts) and the paramesonephric ducts, (also known as Müllerian ducts). The mesonephric duct gives rise to the male seminal vesicles, epididymides and vasa deferentia. The paramesonephric duct gives rise to the female fallopian tubes, uterus, cervix, and upper part of ...
However, a kidney primordium that runs along the intermediate mesoderm does form and links up to the cloaca. This duct is known as the pronephric duct, mesonephric duct or Wolffian duct. While this transient primordium never forms functional nephrons, the duct derived from it is essential to the development of the more complex later kidneys. [1]