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Chondrocytes (/ ˈ k ɒ n d r ə s aɪ t,-d r oʊ-/, [1] from Greek χόνδρος (chondros) ' cartilage ' and κύτος (kytos) ' cell ') are the only cells found in healthy cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans .
The cartilage cells or chondrocytes are contained in cavities in the matrix, called cartilage lacunae; around these, the matrix is arranged in concentric lines as if it had been formed in successive portions around the cartilage cells. This constitutes the so-called capsule of the space.
Isogenous groups differentiate into individual chondrocytes where they continue to produce and deposit extracellular matrix (ECM), lengthening the cartilage and increasing its diameter. [3] [5] This is termed interstitial growth and is one of only two ways cartilage can grow. [4] Cartoon representation of hyaline cartilage with isogenous groups.
Hyaline cartilage is located in the trachea, nose, epiphyseal plate, sternum, and ribs. [2] Hyaline cartilage is covered externally by a fibrous membrane known as the perichondrium. [2] The primary cells of cartilage are chondrocytes, which are in a matrix of fibrous tissue, proteoglycans and glycosaminoglycans. [2] [3]
This requires a hyaline cartilage precursor. There are two centers of ossification for endochondral ossification. The primary center. In long bones, bone tissue first appears in the diaphysis (middle of shaft). Chondrocytes multiply and form trebeculae. Cartilage is progressively eroded and replaced by hardened bone, extending towards the ...
The odontophore is a vesicular cell rich cartilage, consisting of vacuolated cells containing myoglobin, surrounded by a low amount of extra cellular matrix containing collagen. The odontophore contains muscle cells along with the chondrocytes in the case of Lymnaea and other mollusks that graze vegetation. [28]
This hyaline cartilage template expands through both: [8] [9] Interstitial growth Appositional growth Cellular protagonists: Chondrocytes present within the existing cartilage. Chondroblasts that develop from the perichondrium. Mechanism: Chondrocytes proliferate and lay down matrix. Chondroblasts differentiate into chondrocytes and lay down ...
An ossification center is a point where ossification of the hyaline cartilage begins. The first step in ossification is that the chondrocytes at this point become hypertrophic and arrange themselves in rows. [1] The matrix in which they are imbedded increases in quantity, so that the cells become further separated from each other.