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Progressive supranuclear palsy (PSP) is a late-onset neurodegenerative disease involving the gradual deterioration and death of specific volumes of the brain. [ 1 ] [ 2 ] The condition leads to symptoms including loss of balance , slowing of movement , difficulty moving the eyes , and cognitive impairment . [ 1 ]
Progressive supranuclear palsy (PSP) is a type of tauopathy, but the cause is not yet discovered. For PSP unusual phosphorylation for tau protein causes vital protein filaments in the nerve cells to destruct, a phenomenon called "neurofibrillary" degeneration.
PSP has been all over the news—here's what to know about it.
They include multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD). Dementia with Lewy bodies (DLB), may or may not be part of the PD spectrum, but it is increasingly recognized as the second-most common type of neurodegenerative dementia after Alzheimer's disease.
Cerebral palsy, a neural disorder caused by intracranial lesions; Conjugate gaze palsy, a disorder affecting the ability to move the eyes; Erb's palsy, also known as brachial palsy, involving paralysis of an arm; Spinal muscular atrophy, also known as wasting palsy; Progressive supranuclear palsy, a degenerative disease
“The most common dementia for people under 60, FTD can cause challenges in communication, ... progressive supranuclear palsy, is difficulty with looking down or other eye movements.
Very rarely only movement of one eye in one direction is affected. Vertical gaze palsies are often caused by lesions to the midbrain due to a stroke or a tumor. In the case that only downward gaze is affected, the cause is normally progressive supranuclear palsy. [15]
The orthopedic surgeon caused “hundreds of devastating injuries” while displaying signs of having a neurological condition, according to court documents.