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Dutasteride is sometimes used as a component of hormone therapy for transgender women in combination with an estrogen and/or another antiandrogen such as spironolactone. [7] It may be useful for preventing and treating scalp hair loss and can also be used as a general antiandrogen for in those who have issues tolerating spironolactone, though as a α-reductase inhibitor it has limited effects ...
Dutasteride (Avodart) was the second steroidal 5α-reductase approved after finasteride. It is a competitive inhibitor of all three 5α-reductase isoenzymes [ 4 ] and it inhibits types 1 and 2 better than finasteride, leading to it causing further reduction in DHT, with >90% reduced DHT levels following 1 year of oral administration.
Dutasteride (brand name Avodart) inhibits all three 5α-reductase isoenzymes and can decrease DHT levels by 95%. [9] [10] It can also reduce DHT levels in the prostate by 97 to 99% in men with prostate cancer. [11] [12] Epristeride (brand names Aipuliete, Chuanliu) is marketed in China for the treatment of benign prostatic hyperplasia.
Three medications have evidence to support their use in male pattern hair loss: finasteride, dutasteride and minoxidil. [15] They typically work better to prevent further hair loss than to regrow lost hair. [15] They may be used together when hair loss is progressive or further regrowth is desired after 12 months. [16]
Instead of giving cash, you can donate appreciated stocks, avoid capital gains taxes and still claim a tax deduction for the full value of the donation. Plus, charities can sell the stock tax-free ...
This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...
Eating a healthy diet can give you a head start in fighting disease, maintaining a healthy weight and just staying as healthy as possible. Some nutrients can even help you fight off cancer .
In the case of women, mean circulating DHT levels have been found to be about 9 ng/dL (0.3 nmol/L) in premenopausal women and 3 ng/dL (0.1 nmol/L) in postmenopausal women. [5] There was no variation in DHT levels across the menstrual cycle in premenopausal women, which is in contrast to testosterone (which shows a peak at mid-cycle ). [ 5 ]
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