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Ceftriaxone, sold under the brand name Rocephin, is a third-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. [4] These include middle ear infections, endocarditis, meningitis, pneumonia, bone and joint infections, intra-abdominal infections, skin infections, urinary tract infections, gonorrhea, and pelvic inflammatory disease. [4]
[7] [8] In 2009, ceftaroline had completed phase-III clinical trials for community-acquired pneumonia comparing it against ceftriaxone with non-inferior results and similar adverse reaction profile. [6] However, only results for phase-II clinical trials in treatment of complicated skin and skin structure infections have been published. [12]
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
These infections include otitis media, strep throat, pneumonia, urinary tract infections, gonorrhea, and Lyme disease. [5] For gonorrhea typically only one dose is required. [6] In the United States it is a second-line treatment to ceftriaxone for gonorrhea. [5] It is taken by mouth. [5] Common side effects include diarrhea, abdominal pain, and ...
The pneumonia is caused by tiny Mycoplasma pneumoniae bacteria and cases are spiking this year, particularly among preschool-age children, according to the US Centers for Disease Control and ...
Anaerobic bacteria can also be isolated in about 35% of individuals who have nosocomial-acquired aspiration pneumonia [25] and pneumonia associated with tracheostomy with and without mechanical ventilation, [26] where they are often isolated along with Enterobacteriaceae, Pseudomonas spp. and Staphylococcus aureus. It is important that ...
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