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Pyrantel is a medication used to treat a number of parasitic worm infections. [2] This includes ascariasis , hookworm infections , enterobiasis (pinworm infection), trichostrongyliasis , and trichinellosis . [ 2 ]
In dogs and cats, whose gastrointestinal tracts are infected with the tapeworms Dipylidium caninum or Taenia taeniaeformis, respectively; [11] [12] praziquantel is also often used in fixed combination with pyrantel embonate against the roundworms : Toxocara cati and Toxascaris leonina.
Ivermectin and pyrantel pamoate are also effective. The combination of ivermectin 6 μg/kg and pyrantel pamoate at 5.0 mg/kg is 100% efficacious against adult worms in dogs. [13] Human infection in case of cutaneous larva migrans is treated with oral thiabendazole at 500 mg in 4 daily dose. [14]
In humans, treatment is by anthelminthic medications, such as albendazole and mebendazole. [13] Treatment in animals can be done with a variety of anthelminthics. [1] A high-protein diet, supplemental iron, or a blood transfusion may also be necessary. [1] Levamisole and pyrantel pamoate are also used to treat hookworm anemia and hookworm disease.
Ancylostoma caninum is a species of nematode known as a hookworm, which principally infects the small intestine of dogs. [1] [2] [3] The result of A. caninum infection ranges from asymptomatic cases to death of the dog; better nourishment, increasing age, prior A. caninum exposure, or vaccination are all linked to improved survival.
Toxocariasis is an illness of humans caused by the dog roundworm (Toxocara canis) and, less frequently, the cat roundworm (Toxocara cati). [1] These are the most common intestinal roundworms of dogs, coyotes, wolves and foxes and domestic cats, respectively. [2]