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Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. [5] This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections and hydatid disease, among others. [5] It has been used for treatment of giardiasis but is not a preferred agent.
This has a cost of about 2 to 3 cents per person per treatment. [1] This is known as mass drug administration and is often carried out among school-age children. [33] For this purpose, broad-spectrum benzimidazoles such as mebendazole and albendazole are the drugs of choice recommended by WHO. [34]
Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
Toxocariasis is an illness of humans caused by the dog roundworm (Toxocara canis) and, less frequently, the cat roundworm (Toxocara cati). [1] These are the most common intestinal roundworms of dogs, coyotes, wolves and foxes and domestic cats, respectively. [2] Humans are among the many "accidental" or paratenic hosts of these roundworms. [3]
Drugs are frequently used to kill parasites in the host. In earlier times, turpentine was often used for this, but modern drugs do not poison intestinal worms directly. Rather, anthelmintic drugs now inhibit an enzyme that is necessary for the worm to make the substance that prevents the worm from being digested. [citation needed]
A patient will ingest the eggs so the worms can colonize the caecum and colon of the human gut for a short period of time and provide treatment. The beneficial effect is temporary because the worms only live for a few weeks. Because of this short life span, treatments need to be repeated at intervals.
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Ascaricides are drugs to treat ascariasis that is caused by infections with parasitic nematodes (roundworms) of the genus Ascaris (giant intestinal roundworms).The large roundworm of pigs (Ascaris suum) typically infects pigs while Ascaris lumbricoides affects human populations, typically in sub-tropical and tropical areas with poor sanitation.