Ads
related to: lithium nephrotoxicity symptoms in adults- Dosing Info
Get Dosing & Information for
This Long-Acting Treatment Option.
- Treatment Options
Transition Patients to a Treatment
With Fewer Doses a Year.
- Administration Guide
Download Instructions for How
to Administer This LAI.
- Find An Injection Center
Visit Site to Find an
Injection Center for Your Patients.
- Long-Acting Options
Discover Which LAI Treatment Plan
Works Best for Your Patients.
- Safety & Tolerability
Learn About the Safety
of This LAI Treatment.
- Dosing Info
Search results
Results From The WOW.Com Content Network
Lithium toxicity, also known as lithium overdose, is the condition of having too much lithium. Symptoms may include a tremor, increased reflexes, trouble walking, kidney problems, and an altered level of consciousness. Some symptoms may last for a year after levels return to normal. Complications may include serotonin syndrome. [1]
As pituitary function is normal, antidiuretic hormone levels are likely to be abnormal or raised. Polyuria will continue as long as the patient is able to drink. If the patient is unable to drink and is still unable to concentrate the urine, then hypernatremia will ensue with its neurologic symptoms.
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances , both toxic chemicals and medications , on kidney function . [ 1 ] There are various forms, [ 2 ] and some drugs may affect kidney function in more than one way.
This constellation of symptoms contrasts with the classical presentation of nephrotic syndrome (excessive proteinuria >3.5 g/day, low plasma albumin levels (hypoalbuminemia) <3 g/L, generalized edema, and hyperlipidemia). [8] [10] Signs and symptoms that are consistent with nephritic syndrome include: Hematuria (red blood cells in the urine) [11]
Acute tubular necrosis (ATN) is a medical condition involving the death of tubular epithelial cells that form the renal tubules of the kidneys.Because necrosis is often not present, the term acute tubular injury (ATI) is preferred by pathologists over the older name acute tubular necrosis (ATN). [1]
Kidney disease, or renal disease, technically referred to as nephropathy, is damage to or disease of a kidney. Nephritis is an inflammatory kidney disease and has several types according to the location of the inflammation.
The various symptoms of acute kidney injury result from the various disturbances of kidney function that are associated with the disease. Accumulation of urea and other nitrogen-containing substances in the bloodstream lead to a number of symptoms, such as fatigue , loss of appetite , headache , nausea , and vomiting . [ 6 ]
Lithium has a plethora of proposed molecular targets: Lithium both directly and indirectly inhibits GSK3β (glycogen synthase kinase 3β) which results in the activation of mTOR. This leads to an increase in neuroprotective mechanisms by facilitating the Akt signaling pathway. [110] GSK-3β is a downstream target of monoamine systems.
Ad
related to: lithium nephrotoxicity symptoms in adults