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Side effects of nandrolone decanoate may include symptoms of masculinization like acne, increased hair growth, and voice changes. [3] The medication is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).
[8] [15] Nandrolone has strong anabolic effects and weak androgenic effects, which give them a mild side effect profile and make them especially suitable for use in women and children. [8] [15] [16] There are metabolites of Nandrolone that act as long-lasting prodrugs in the body, [8] such as 5α-Dihydronandrolone.
5-ARIs are generally well tolerated in both men and women and produce few side effects. [ 19 ] [ 20 ] However, they have been found to have some risks in studies with men, including slightly increased risks of decreased libido , erectile dysfunction , ejaculatory dysfunction , infertility , breast tenderness , gynecomastia , depression ...
[18] [19] Nandrolone decanoate is approved for this use. [20] Although they have been indicated for this indication, AAS saw very little use for this purpose due to their virilizing side effects. [18] [21] Aiding weight gain following surgery or physical trauma, during chronic infection, or in the context of unexplained weight loss. [22] [23]
Due to its side effects, amitriptyline isn’t commonly used as a first-line treatment for depression. Viorel Kurnosov/istockphoto Another well-known TCA is doxepin, sold under the name Silenor.
These side effects may occur in as many as 90% of men treated with bicalutamide monotherapy, [29] but gynecomastia is generally reported to occur in 70 to 80% of patients. [30] In the EPC trial, at a median follow-up of 7.4 years, breast pain and gynecomastia respectively occurred in 73.6% and 68.8% of men treated with 150 mg/day bicalutamide ...
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