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If most of the flux goes through J2(a) then the pathway behaves like a simple linear change, where flux control on J3 is negligible and control is shared between J1 and J2. The other extreme is when most of the flux goes through J3 (b). This makes J2 highly sensitive to changes in J1 and J3 resulting is very high flux control, often greater ...
Regulation of biological processes occurs when any process is modulated in its frequency, rate or extent. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
A simpler and more direct way to explain the fundamentals of the "hierarchical organisation of life", was introduced in Ecology by Odum and others as the "Simon's hierarchical principle"; [17] Simon [18] emphasized that hierarchy "emerges almost inevitably through a wide variety of evolutionary processes, for the simple reason that hierarchical ...
The Systems Biology Graphical Notation (SBGN) is a standard graphical representation intended to foster the efficient storage, exchange and reuse of information about signaling pathways, metabolic networks, and gene regulatory networks amongst communities of biochemists, biologists, and theoreticians.
Biological organization spans several scales and are determined based different structures depending on what the system is. [1] Examples of biological systems at the macro scale are populations of organisms. On the organ and tissue scale in mammals and other animals, examples include the circulatory system, the respiratory system, and the ...
Cellular compartments in cell biology comprise all of the closed parts within the cytosol of a eukaryotic cell, usually surrounded by a single or double lipid layer membrane. These compartments are often, but not always, defined as membrane-bound organelles. The formation of cellular compartments is called compartmentalization.
In biology, pairwise interactions have historically been the focus of intense study. With the recent advances in network science , it has become possible to scale up pairwise interactions to include individuals of many species involved in many sets of interactions to understand the structure and function of larger ecological networks . [ 29 ]
In human genetics, Haplogroup J-M172 or J2 [Phylogenetics 1] is a Y-chromosome haplogroup which is a subclade (branch) of haplogroup J-M304. [ Phylogenetics 2 ] Haplogroup J-M172 is common in modern populations in Western Asia , Central Asia , South Asia , Southern Europe , Northwestern Iran and North Africa .