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Dutasteride is sometimes used as a component of hormone therapy for transgender women in combination with an estrogen and/or another antiandrogen such as spironolactone. [7] It may be useful for preventing and treating scalp hair loss and can also be used as a general antiandrogen for in those who have issues tolerating spironolactone, though as a α-reductase inhibitor it has limited effects ...
A 2017 population-based, matched-cohort study of 93,197 men aged 66 years and older with BPH found that finasteride and dutasteride were associated with a significantly increased risk of depression (HR Tooltip Hazard ratio, 1.94; 95% CI Tooltip Confidence interval, 1.73–2.16) and self-harm (HR, 1.88; 95% CI, 1.34–2.64) during the first 18 ...
This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...
Plasma centers pay anywhere from $20 to $100 per donation, based on your location, weight and how often you donate. You can donate plasma for money twice within per week, but not more than once in ...
Hair today, gone tomorrow can make any man rush to their healthcare provider for a solution to regain their once-full head of hair. But with so many treatment options out there, how’s a guy ...
A humidifier can be used to prevent low indoor humidity during winter (especially with indoor heating), and dry season. [6] Commonly, patients with seborrhoeic dermatitis experience mild redness, scaly skin lesions and in some cases hair loss. [7] Low humidity can cause adverse health effects and may cause atopic dermatitis, [8] and seborrhoeic ...
Upon analysis, scientists found that participants who stayed on standard statin treatment for their lifetime increased their quality-adjusted life years by 0.24-0.70, and those on higher-intensity ...
Dutasteride has also been found to inhibit 5α-R3, in vitro, with IC50=0.33 nM. [6] The 2,5-difluorophenyl side chain on the D-ring of the compound shows significant lipophilic features and as increased lipophilicity enhances the potency of the compounds binding at pocket site, its potency is much greater than of finasteride.