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Cerebrospinal fluid (CSF) flow MRI is used to assess pulsatile CSF flow both qualitatively and quantitatively. Time-resolved 2D phase-contrast MRI with velocity encoding is the most common method for CSF analysis. [ 1 ]
Contrast-enhanced brain MRI with sagittal reformats can assess for the following: [6] [8] Subdural fluid collections; Enhancement of the meninges; Engorgement of venous structures; Pituitary swelling; Sagging of the brain; For suspected spinal CSF leaks, spine imaging can be used to guide treatment. [8]
In CT scan, subdural hygroma will have same density as the normal CSF. Meanwhile, in MRI, subdural hygroma will have same intensity with CSF. If iodinated contrast is administered during CT scan, the hygroma will produce high density because of the contrast at 120 kVp. However, at 190 kVp, hygroma with contrast will have intermediate density. [2]
If a leak is identified, a beta-2 transferrin test of the leaking fluid, when positive, is highly specific and sensitive for the detection for CSF leakage. [34] Medical imaging such as CT scans and MRI scans can be used to investigate for a presumed CSF leak when no obvious leak is found but low CSF pressure is identified. [35]
Fluid-attenuated inversion recovery (FLAIR) is a magnetic resonance imaging sequence with an inversion recovery set to null fluids. For example, it can be used in brain imaging to suppress cerebrospinal fluid (CSF) effects on the image, so as to bring out the periventricular hyperintense lesions, such as multiple sclerosis (MS) plaques. [1]
Radionuclide cisternography may be used to diagnose a spinal cerebrospinal fluid leak. CSF pressure is measured and imaged over 24 hours. [2] A radionuclide (radioisotope) is injected by lumbar puncture (spinal tap) into the cerebral spinal fluid to determine if there is abnormal CSF flow within the brain and spinal canal which can be altered by hydrocephalus, Arnold–Chiari malformation ...
The first MR images of a human brain were obtained in 1978 by two groups of researchers at EMI Laboratories led by Ian Robert Young and Hugh Clow. [1] In 1986, Charles L. Dumoulin and Howard R. Hart at General Electric developed MR angiography, [2] and Denis Le Bihan obtained the first images and later patented diffusion MRI. [3]
A pseudomeningocele is an abnormal collection of cerebrospinal fluid (CSF) that communicates with the CSF space around the brain or spinal cord.In contrast to a meningocele, in which the fluid is surrounded and confined by dura mater, in a pseudomeningocele, the fluid has no surrounding membrane, but is contained in a cavity within the soft tissues.