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  2. Naltrexone/bupropion - Wikipedia

    en.wikipedia.org/wiki/Naltrexone/bupropion

    Each Contrave tablet contains 8 mg naltrexone and 90 mg bupropion. [12] Once full dosing is reached (after 4 weeks of administration), the total dosage of Contrave for treating overweight or obesity is two tablets twice daily or 32 mg naltrexone and 360 mg bupropion per day. [12]

  3. Naltrexone - Wikipedia

    en.wikipedia.org/wiki/Naltrexone

    Naltrexone at a dose of 100 mg/day has been found to achieve 87% and 92% brain occupancy of the KOR in different studies. [85] [84] [86] Per simulation, a lower dose of naltrexone of 25 mg/day might be expected to achieve around 60% brain occupancy of the KOR but still close to 90% occupancy of the MOR. [84]

  4. Mounjaro for Weight Loss: What You Need to Know Before ... - AOL

    www.aol.com/mounjaro-weight-loss-know-starting...

    Mounjaro isn’t FDA-approved for weight loss. It’s approved as a diabetes drug and prescribed off-label for weight loss. Zepbound has the same active ingredient and is FDA-approved for weight loss.

  5. Anti-obesity medication - Wikipedia

    en.wikipedia.org/wiki/Anti-obesity_medication

    [1] [2] [3] Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for ...

  6. Low-dose naltrexone - Wikipedia

    en.wikipedia.org/wiki/Low-dose_naltrexone

    Multiple studies have shown that low-dose naltrexone has promise as a treatment for chronic pain, some autoimmune disorders and cancers. [7] [8] [9] As of 2014, no peer-reviewed studies supporting low-dose naltrexone for multiple sclerosis (MS) have been published. [10] [11] Clinical trials for treatment of fibromyalgia were initiated in 2021. [12]

  7. Opioid antagonist - Wikipedia

    en.wikipedia.org/wiki/Opioid_antagonist

    A course of low-dose naltrexone is thus often used as the final step in the treatment of opioid addiction after the patient has been weaned off the substitute agonist such as methadone or buprenorphine, in order to restore homeostasis and minimize the risk of post acute withdrawal syndrome once the maintenance agonist has been withdrawn.